Three core research programs in drug delivery, space medicine, and smart medical devices.
Our laboratory develops innovative polymer drug delivery platforms and next-generation smart medical devices targeting diseases in both terrestrial and space environments.
Cancer vaccines for overcoming immunotherapy resistance, organelle-targeting technology for mitochondrial re-engineering, and intelligent polymer nanoparticles for sequential release of gene therapeutics and chemotherapeutics in the tumor microenvironment.
Utilizing space-accelerated aging environments for discovering anti-aging targets and screening therapeutics for neurodegenerative and muscular diseases. Developing countermeasures against space radiation and microgravity-induced cellular dysfunction.
Designing implantable medical devices with stimuli-responsive polymer coatings that release drugs on-demand in response to ultrasound, magnetic fields, or light. Targeting liver, biliary, and pancreatic cancers with image-guided energy delivery probes.